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1

Integrated In Vitro – In Silico Screening Strategy for the Discovery of Antibacterial Compounds

Nybond, Susanna, Ghemtio, Leo, Nawrot, Dorota A., Karp, Matti, Xhaard, Henri, Tammela, Päivi

Journal:

Assay and Drug Development Technologies

Year:

2015

Language:

english

File:

PDF, 524 KB

english, 2015

2

Screening of natural compounds and their derivatives as potential protein kinase C inhibitors

Päivi Tammela, Elina Ekokoski, Arturo García-Horsman, Virpi Talman, Moshe Finel, Raimo Tuominen, Pia Vuorela

Journal:

Drug Development Research

Year:

2004

Language:

english

File:

PDF, 219 KB

english, 2004

3

Synthesis and Biological Evaluation of 2-Aminobenzothiazole and Benzimidazole Analogs Based on the Clathrodin Structure

Montalvão, Sofia, Leino, Teppo O., Kiuru, Paula S., Lillsunde, Katja-Emilia, Yli-Kauhaluoma, Jari, Tammela, Päivi

Journal:

Archiv der Pharmazie

Year:

2016

Language:

english

File:

PDF, 785 KB

english, 2016

4

Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors

Jakopin, Žiga, Ilaš, Janez, Barančoková, Michaela, Brvar, Matjaž, Tammela, Päivi, Sollner Dolenc, Marija, Tomašič, Tihomir, Kikelj, Danijel

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.12 MB

english, 2017

5

Hydrophobic derivatives of 5-(hydroxymethyl)isophthalic acid that selectively induce apoptosis in leukemia cells but not in fibroblasts

Anna Galkin, Anu Surakka, Gustav Boije af Gennäs, Timo Ruotsalainen, Kari Kreander, Päivi Tammela, Kaarina Sivonen, Jari Yli-Kauhaluoma, Pia Vuorela

Journal:

Drug Development Research

Year:

2008

Language:

english

File:

PDF, 170 KB

english, 2008

6

Development and validation of a time-resolved fluorometric immunoassay for screening of antichlamydial activity using a genus-specific europium-conjugated antibody

Päivi Tammela, Joni Alvesalo, Laura Riihimäki, Sari Airenne, Maija Leinonen, Pertti Hurskainen, Kristian Enkvist, Pia Vuorela

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 415 KB

english, 2004

7

Assessing the data quality in predictive toxicology using a panel of cell lines and cytotoxicity assays

Leena Pohjala, Päivi Tammela, Swapan K. Samanta, Jari Yli-Kauhaluoma, Pia Vuorela

Journal:

Analytical Biochemistry

Year:

2007

Language:

english

File:

PDF, 334 KB

english, 2007

8

HPLC micro-fractionation coupled to a cell-based assay for automated on-line primary screening of calcium antagonistic components in plant extracts

Päivi Tammela, Tero Wennberg, Heikki Vuorela, Pia Vuorela

Journal:

Analytical and Bioanalytical Chemistry

Year:

2004

Language:

english

File:

PDF, 263 KB

english, 2004

9

Frequency and clinical correlates of radiographic patterns of bronchopulmonary dysplasia in very low birth weight infants by term age

Elina Hyödynmaa, Päivi Korhonen, Sirkku Ahonen, Tiina Luukkaala, Outi Tammela

Journal:

European Journal of Pediatrics

Year:

2012

Language:

english

File:

PDF, 133 KB

english, 2012

10

Comparison of transgenicGerbera hybridalines and traditional varieties shows no differences in cytotoxicity or metabolic fingerprints

Miia Marika Ainasoja, Leena Lyydia Pohjala, Päivi Sirpa Marjaana Tammela, Panu Juhani Somervuo, Pia Maarit Vuorela, Teemu Heikki Teeri

Journal:

Transgenic Research

Year:

2008

Language:

english

File:

PDF, 263 KB

english, 2008

11

Microplate screening assay to identify inhibitors of human catechol-O-methyltransferase

Mika Kurkela, Antti Siiskonen, Moshe Finel, Päivi Tammela, Jyrki Taskinen, Pia Vuorela

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 228 KB

english, 2004

12

In-vitro mutagenic potential and effect on permeability of co-administered drugs across Caco-2 cell monolayers of Rubus idaeus and its fortified fractions

Kari Kreander, Anna Galkin, Satu Vuorela, Päivi Tammela, Leena Laitinen, Marina Heinonen, Pia Vuorela

Journal:

Journal of Pharmacy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 297 KB

english, 2006

13

Identification of Alphavirus Inhibitors by Using Virus-Based Assays and a Chikungunya Replicon Cell Line

Tero Ahola, Leena Pohjala, Pasi Kaukinen, Age Utt, Margus Varjak, Andres Merits, Päivi Tammela

Journal:

Antiviral Research

Year:

2011

Language:

english

File:

PDF, 79 KB

english, 2011

14

Effects of simple aromatic compounds and flavonoids on Ca2+ fluxes in rat pituitary GH4C1 cells

Jari Summanen, Pia Vuorela, Jussi-Pekka Rauha, Päivi Tammela, Krista Marjamäki, Michael Pasternack, Kid Törnquist, Heikki Vuorela

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 160 KB

english, 2001

15

Effect of Concomitant Administration of Clodronate and Estramustine Phosphate on their Bioavaibility in Patients with Metastasized Prostate Cancer

Timo Kylmälä, Päivi Castrén-Kortekangas, Jaakko Seppänen, Pauli Ylitalo, Teuvo L. J. Tammela

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1996

Language:

english

File:

PDF, 423 KB

english, 1996

16

An unexpected cause of gastric perforation in a term-born neonate

Päivi Korhonen, Merja Helminen, Tarja Iber, Alar Abram, Outi Tammela

Journal:

Acta Paediatrica

Year:

2007

Language:

english

File:

PDF, 263 KB

english, 2007

17

Predictors of delayed first voiding in newborn

Tuomo Vuohelainen, Riitta Ojala, Anita Virtanen, Päivi Holm, Outi Tammela

Journal:

Acta Paediatrica

Year:

2008

Language:

english

File:

PDF, 269 KB

english, 2008

18

Permeability characteristics and membrane affinity of flavonoids and alkyl gallates in Caco-2 cells and in phospholipid vesicles

Päivi Tammela, Leena Laitinen, Anna Galkin, Tero Wennberg, Robert Heczko, Heikki Vuorela, J.Peter Slotte, Pia Vuorela

Journal:

Archives of Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 338 KB

english, 2004

19

Miniaturisation and validation of a cell-based assay for screening of Ca2+ channel modulators

Päivi Tammela, Pia Vuorela

Journal:

Journal of Biochemical and Biophysical Methods

Year:

2004

Language:

english

File:

PDF, 186 KB

english, 2004

20

Preoperative embolization of giant sacrococcygeal teratoma in a premature newborn

Tuija Terhikki Lahdes-Vasama, Päivi H. Korhonen, Janne M. Seppänen, Outi K. Tammela, Tarja Iber

Journal:

Journal of Pediatric Surgery

Year:

2011

Language:

english

File:

PDF, 551 KB

english, 2011

21

Ent-kauren-19-oic acid derivatives from the stem bark of Croton pseudopulchellus Pax

Moses K. Langat, Neil R. Crouch, Leena Pohjala, Päivi Tammela, Peter J. Smith, Dulcie A. Mulholland

Journal:

Phytochemistry Letters

Year:

2012

Language:

english

File:

PDF, 221 KB

english, 2012

22

Similarity Based Virtual Screening: A Tool for Targeted Library Design

Alvesalo, Joni K. O., Siiskonen, Antti, Vainio, Mikko J., Tammela, Päivi S. M., Vuorela, Pia M.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 93 KB

english, 2006

23

Antimicrobial assay optimization and validation for HTS in 384-well format using a bioluminescent E. coli K-12 strain

Nybond, Susanna, Karp, Matti, Tammela, Päivi

Journal:

European Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 578 KB

english, 2013

24

Utilization of in situ ELISA method for examining Trk receptor phosphorylation in cultured cells

Antila, Hanna, Autio, Henri, Turunen, Laura, Harju, Kirsi, Tammela, Päivi, Wennerberg, Krister, Yli-Kauhaluoma, Jari, Huttunen, Henri J., Castrén, Eero, Rantamäki, Tomi

Journal:

Journal of Neuroscience Methods

Year:

2014

Language:

english

File:

PDF, 1023 KB

english, 2014

25

Neurocognitive Test Profiles of Extremely Low Birth Weight Five-Year-Old Children Differ According to Neuromotor Status

Korkman, Marit, Mikkola, Kaija, Ritari, Niina, Tommiska, Viena, Salokorpi, Teija, Haataja, Leena, Tammela, Outi, Pääkkönen, Leena, Olsén, Päivi, Fellman, Vineta

Journal:

Developmental Neuropsychology

Year:

2008

Language:

english

File:

PDF, 182 KB

english, 2008

26

Perinatal immunoproteins predict the risk of cerebral palsy in preterm children

Kaukola, Tuula, Kallankari, Hanna, Tuimala, Jarno, Olsén, PäIvi, Tammela, Outi, Kingsmore, Stephen F., Hallman, Mikko

Journal:

Annals of Medicine

Year:

2013

Language:

english

File:

PDF, 169 KB

english, 2013

27

Tocopherols, tocotrienols and fatty acids as indicators of natural ageing in Pinus sylvestris seeds

Tammela, Päivi, Salo-Väänänen, Pirjo, Laakso, Into, Hopia, Anu, Vuorela, Heikki, Nygren, Markku

Journal:

Scandinavian Journal of Forest Research

Year:

2005

Language:

english

File:

PDF, 127 KB

english, 2005

28

Synthesis and biological evaluation of 2-arylbenzimidazoles targeting Leishmania donovani

Keurulainen, Leena, Siiskonen, Antti, Nasereddin, Abedelmajeed, Kopelyanskiy, Dmitry, Sacerdoti-Sierra, Nina, Leino, Teppo O., Tammela, Päivi, Yli-Kauhaluoma, Jari, Jaffe, Charles L., Kiuru, Paula

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.90 MB

english, 2015

29

Exploring the structure–activity relationships of ABCC2 modulators using a screening approach

Wissel, Gloria, Kudryavtsev, Pavel, Ghemtio, Leo, Tammela, Päivi, Wipf, Peter, Yliperttula, Marjo, Finel, Moshe, Urtti, Arto, Kidron, Heidi, Xhaard, Henri

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 2.27 MB

english, 2015

30

Aggregating Behavior of Phenolic Compounds — A Source of False Bioassay Results?

Pohjala, Leena, Tammela, Päivi

Journal:

Year:

2012

Language:

english

File:

PDF, 273 KB

english, 2012

31

Very low birthweight bronchopulmonary dysplasia survivors show no substantial association between lung function and current inflammatory markers

Suursalmi, Piia, Kopeli, Tarja, Korhonen, Päivi, Lehtimäki, Lauri, Nieminen, Riina, Luukkaala, Tiina, Moilanen, Eeva, Korppi, Matti, Paassilta, Marita, Tammela, Outi

Journal:

Acta Paediatrica

Year:

2015

Language:

english

File:

PDF, 102 KB

english, 2015

32

Inhibitors of Alphavirus Entry and Replication Identified with a Stable Chikungunya Replicon Cell Line and Virus-Based Assays

Pohjala, Leena, Utt, Age, Varjak, Margus, Lulla, Aleksei, Merits, Andres, Ahola, Tero, Tammela, Päivi, Poh, Lisa Ng Fong

Journal:

Year:

2011

Language:

english

File:

PDF, 534 KB

english, 2011

33

Bioluminescent whole-cell reporter gene assays as screening tools in the identification of antimicrobial natural product extracts

Nybond, Susanna, Karp, Matti, Yrjönen, Teijo, Tammela, Päivi

Journal:

Journal of Microbiological Methods

Year:

2015

Language:

english

File:

PDF, 392 KB

english, 2015

34

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2- d ]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site

Tomašič, Tihomir, Katsamakas, Sotirios, Hodnik, Žiga, Ilaš, Janez, Brvar, Matjaž, Solmajer, Tom, Montalvão, Sofia, Tammela, Päivi, Banjanac, Mihailo, Ergović, Gabrijela, Anderluh, Marko, Mašič, Lucija

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

35

Exploring Marine Resources for Bioactive Compounds

Kiuru, Paula, DʼAuria, M., Muller, Christian, Tammela, Päivi, Vuorela, Heikki, Yli-Kauhaluoma, Jari

Journal:

Year:

2014

Language:

english

File:

PDF, 311 KB

english, 2014

36

Acetate-Derived Metabolites from the Brown Alga Lobophora variegata

Gutiérrez-Cepeda, Adrián, Fernández, José J., Norte, Manuel, Montalvão, Sofia, Tammela, Päivi, Souto, María L.

Journal:

Journal of Natural Products

Year:

2015

Language:

english

File:

PDF, 770 KB

english, 2015

37

N -Phenyl-4,5-dibromopyrrolamides and N -Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation

Zidar, Nace, Macut, Helena, Tomašič, Tihomir, Brvar, Matjaž, Montalvão, Sofia, Tammela, Päivi, Solmajer, Tom, Peterlin Mašič, Lucija, Ilaš, Janez, Kikelj, Danijel

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.03 MB

english, 2015

38

Baltic cyanobacteria – a source of biologically active compounds

Mazur-Marzec, Hanna, Błaszczyk, Agata, Felczykowska, Agnieszka, Hohlfeld, Natalia, Kobos, Justyna, Toruńska-Sitarz, Anna, Devi, Prabha, Montalvão, Sofia, D’souza, Lisette, Tammela, Päivi, Mikosik, Ann

Journal:

European Journal of Phycology

Year:

2015

Language:

english

File:

PDF, 337 KB

english, 2015

39

Cell-based bioreporter assay coupled to HPLC micro-fractionation in the evaluation of antimicrobial properties of the basidiomycete fungus Pycnoporus cinnabarinus

Järvinen, Päivi, Nybond, Susanna, Marcourt, Laurence, Ferreira Queiroz, Emerson, Wolfender, Jean-Luc, Mettälä, Aila, Karp, Matti, Vuorela, Heikki, Vuorela, Pia, Hatakka, Annele, Tammela, Päivi

Journal:

Pharmaceutical Biology

Year:

2016

Language:

english

File:

PDF, 930 KB

english, 2016

40

New N-Phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATPase Inhibitors of DNA Gyrase

Zidar, Nace, Tomašič, Tihomir, Macut, Helena, Sirc, Anja, Brvar, Matjaž, Montalvão, Sofia, Tammela, Päivi, Ilaš, Janez, Kikelj, Danijel

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

41

Asthma and atopic dermatitis in children born moderately and late preterm

Haataja, Paula, Korhonen, Päivi, Ojala, Riitta, Hirvonen, Mikko, Paassilta, Marita, Gissler, Mika, Luukkaala, Tiina, Tammela, Outi

Journal:

European Journal of Pediatrics

Year:

2016

Language:

english

File:

PDF, 417 KB

english, 2016

42

Inflammatory activity at school age in very low birth weight bronchopulmonary dysplasia survivors

Korhonen, Päivi H., Suursalmi, Piia H., Kopeli, Tarja, Nieminen, Riina, Lehtimäki, Lauri, Luukkaala, Tiina, Korppi, Matti, Saari, Antti, Moilanen, Eeva, Tammela, Outi K.T.

Journal:

Pediatric Pulmonology

Year:

2015

Language:

english

File:

PDF, 75 KB

english, 2015

43

Cerebral Palsy Among Children Born Moderately and Late Preterm

Hirvonen, Mikko, Ojala, Riitta, Korhonen, Päivi, Haataja, Paula, Eriksson, Kai, Gissler, Mika, Luukkaala, Tiina, Tammela, Outi

Journal:

Obstetric and Gynecologic Survey

Year:

2015

Language:

english

File:

PDF, 78 KB

english, 2015

44

Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors

Gjorgjieva, Marina, Tomasic, Tihomir, Barančokova, Michaela, Katsamakas, Sotirios, Ilaš, Janez, Tammela, Päivi, Peterlin Mašič, Lucija, Kikelj, Danijel

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 957 KB

english, 2016

45

Synthesis and biological evaluation of crown ether acyl derivatives

Febles, Martín, Montalvão, Sofía, Crespín, Guillermo Díaz, Norte, Manuel, Padrón, José M., Tammela, Päivi, Fernández, José J., Daranas, Antonio Hernández

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 293 KB

english, 2016

46

Antibacterial profiling of abietane-type diterpenoids

Helfenstein, Andreas, Vahermo, Mikko, Nawrot, Dorota A., Demirci, Fatih, İşcan, Gökalp, Krogerus, Sara, Yli-Kauhaluoma, Jari, Moreira, Vânia M., Tammela, Päivi

Journal:

Bioorganic & Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 543 KB

english, 2016

47

Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors

Tomašič, Tihomir, Mirt, Matic, Barančoková, Michaela, Ilaš, Janez, Zidar, Nace, Tammela, Päivi, Kikelj, Danijel

Journal:

Bioorganic & Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.66 MB

english, 2016

48

Inhibition of BCRP and MRP2 by natural compounds and their derivatives

Sjöstedt, Noora, Holvikari, Kira, Tammela, Päivi, Kidron, Heidi

Journal:

Molecular Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 1.29 MB

english, 2016

49

Analyzing user-generated online content for drug discovery: development and use of MedCrawler

Helfenstein, Andreas, Tammela, Päivi

Journal:

Year:

2016

Language:

english

File:

PDF, 470 KB

english, 2016

50

Prospective Randomized Trial of Interferon Alfa-2a Plus Vinblastine Versus Vinblastine Alone in Patients With Advanced Renal Cell Cancer

Pyrhönen, Seppo, Salminen, Eeva, Ruutu, Mirja, Lehtonen, Timo, Nurmi, Martti, Tammela, Teuvo, Juusela, Harri, Rintala, Erkki, Hietanen, Päivi, Kellokumpu-Lehtinen, Pirko-Liisa

Journal:

Journal of Clinical Oncology

Year:

1999

Language:

english

File:

PDF, 118 KB

english, 1999

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